EAST LANSING, Mich. — An alliance composed of Michigan’s top three research universities, two leading health care systems, and state and local health agencies will join together in a national research project to study how the environment affects the health and development of children. 

Funded by an $18.5 million research contract from the National Institutes of Health (NIH), the National Children’s Study (NCS) will monitor more than 100,000 children nationally from before birth to age 21. In Michigan, researchers will recruit and monitor approximately 1,000 participants in Wayne County in the initial phase of the program. 

Michigan State University will lead Michigan’s role in the project, which is believed to be the most ambitious children’s health study of its kind in the nation. 

Project collaborators include MSU, University of Michigan, Wayne State University, Children’s Hospital of Michigan, Henry Ford Health System, Michigan Department of Community Health (MDCH), and Wayne County and city of Detroit health departments. 

Directing the Michigan project will be Nigel Paneth, MSU professor of epidemiology, and pediatrics and human development. 

“No children’s health study of this size or scope has ever been undertaken,” Paneth said. “The results should provide critical information about environmental influences and effects on the health of children. 

“Environmental influences are broadly defined,” he added. “We are examining the effects of environmental toxins, nutrition and family and societal structures. 

“By studying children through several phases of growth and development, including their development before birth, we will be better able to understand the role of these factors on health and disease.”

"The participation of MSU, U-M and Wayne State in the National Children’s Study is one of many examples of collaboration between the three universities that make up the University Research Corridor," said MSU President Lou Anna K. Simon. 

The URC is designed to promote and leverage the schools’ collective assets and to encourage collaboration among the universities and the state. Its ultimate goal is to accelerate statewide economic development.

The first phase of the Michigan part of the National Children's Study focuses on Wayne County. Participant recruitment is expected to begin sometime in 2009.

In the future, it is anticipated that the study will include four other Michigan counties that were selected to be among the 105 counties representing the United States in the NCS: Genesee, Grand Traverse, Lenawee and Macomb counties. 

Planning for this project began in 2002 when MSU and the other partners formed the Michigan Alliance for the National Children’s Study (MANCS). The idea, said Paneth, was that each institution brings unique skills to the table. 

“The structure of MANCS reflects a sustained collaborative effort among Michigan State, Wayne State, University of Michigan and Henry Ford which collectively account for 96 percent of NIH research dollars in Michigan,” Paneth said. 

Each institution will play a specific role in the study. 

• U-M will be responsible for enrolling and interviewing study participants and assessing postnatal child development.
   
• WSU will oversee the assessment and care of pregnant women.
   
• Children’s Hospital of Michigan will serve as the repository for biological samples.
   
• Henry Ford Health System will serve as the repository for environmental samples and will perform medical examinations of children.
   
• MSU will coordinate the overall work of the study and house the project at its East Lansing campus. MSU Extension will help develop community support for the study.
   
• MDCH will provide information related to live birth characteristics and locations in Wayne County. 

“It’s important that Michigan be a part of the largest and most comprehensive national study of child health ever mounted,” Paneth said. “But we also expect that issues especially important to the health of Michigan children will be addressed, leading to new ways of treating and preventing disease in our children and to new public health programs in our state.”

Listen to a podcast with Paneth at http://spartanpodcast.com/?p=322. 

Visit the NIH National Children’s Study Web site at www.nationalchildrensstudy.gov. 

ADDITIONAL CONTACT INFORMATION: 

Michigan State University:
Nigel Paneth, Epidemiology: (517) 353-8623, ext. 112; paneth@epi.msu.edu
(unavailable Oct. 2-10)      
Dele Davies, Pediatrics and Human Development: (517) 355-3308, daviesde@msu.edu 

University of Michigan
Daniel Keating, U-M Center for Human Growth and Development: (734) 660-2209, keatingd@umich.edu
Diane Swanbrow, U-M News: (734) 647-9069, swanbrow@umich.edu

Wayne State University
Hilary Ratner, Vice President for Research: (313) 577-5600, hilary.ratner@wayne.edu
Julie O’Connor, Research Communications, (313) 577-8845, julie.oconnor@wayne.edu  

Children’s Hospital of Michigan and Wayne State University
William Lyman, Children’s Research Center of Michigan: (313) 745-2400, wlyman@med.wayne.edu
Rosie Reebel, Media Relations: (313) 745-4996, rreebel@dmc.org  

Henry Ford Health System
Charles Barone, Department of Pediatrics, Henry Ford Medical Group: (313) 874-9591, cbarone1@hfhs.org
David Olejarz, Public Relations, Henry Ford Health System: (313) 874-4094, dolejar1@hfhs.org  

Michigan Department of Community Health
Violanda Grigorescu, Division of Genomics, Perinatal Health and Chronic Epidemiology: (517) 335-9166, grigorescuv@michigan.gov  

Wayne County Health Department
Anahid Kulwicki, Health and Human Services: (313) 224-0810, akulwick@co.wayne.mi.us
Dennis Niemiec, Communications: (313) 224-5575, dniemiec@co.wayne.mi.us  

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